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Electrical synapses, synchrony and rhythm generation in the mammalian centra…

演讲者:Dr. David Spanswick                 英国沃里克大学医学院生物学系,分子神经科学教授   时   间:07年04月12日(周四)上午9:00 主持人:韩济生院士,教授,北京大学神经科学研究所 地   点:神经科学研究所会议室(中心实验楼北小院底层) 主  办:神经科学研究所   Selected publication: 1)      Spanswick, D., Smith, M.A., Groppi, V.E., Logan, S.D. and Ashford, M.L.J. (1997).  Leptin inhibits hypothalamic neurones by activation of ATP-sensitive potassium channels.  Nature, 390: 521-525 . 2)      Dickinson, T., Lee, K., Spanswick D. & Munro F.E. (2003).  Leading the charge--pioneering treatments in the fight against neuropathic pain.  Trends in Pharmacological Sciences (TIPS). 24(11):555-557. 3)      Whyment, A.D., Wilson, J.M.M., Renaud, L.P. & Spanswick, D. (2004)  Bilateral GABA receptor-mediated synaptic modulation of neonatal rat sympathetic preganglionic neurones in vitro.  Journal of Physiology 555 (1): 189-203. 4)      van Den Top, M., Lee, K., Whyment, A., Blanks, A and Spanswick, D. (2004) Orexigen-sensitive NPY/AgRP pacemaker neurons in the hypothalamic arcuate nucleus.  Nature Neuroscience 7 (5): 493-494 5)      Spanswick D, Renaud LP. (2005). Angiotensin II induces calcium-dependent rhythmic activity in a subpopulation of rat hypothalamic median preoptic nucleus neurons. J Neurophysiol., 93(4):1970-6. 6)      Lee K, Spanswick D (2006). Pain.  Semin Cell Dev Biol., 17(5):541-3. 7)      Zhao FY, Spanswick D, Martindale JC, Reeve AJ, Chessell IP. (2007). GW406381, a novel COX-2 inhibitor, attenuates spontaneous ectopic discharge in sural nerves of rats following chronic constriction injury.  Pain;128(1-2):78-87 8)      van den Top M, Spanswick D. (2006).  Integration of metabolic stimuli in the hypothalamic arcuate nucleus.  Prog Brain Res., 153:141-54. 9)      Whyment AD, Blanks AM, Lee K, Renaud LP, Spanswick D. (2006). Histamine excites neonatal rat sympathetic preganglionic neurons in vitro via activation of H1 receptors.  J Neurophysiol, 95(4):2492-500.